We congratulate Micah Johnson (GS 2nd) for being awarded a prestigious NSF graduate fellowship!
Latest interview to Prof Monti on the topic of brain death and its criteria:
- Los Angeles Times (online): What constitutes brain death?
- Los Angeles Times (print): Criteria vary for brain death diagnosis.
- Definition of brain death depends on hospital, study finds.
Lutkenhoff E.S., Chiang J., Tshibanda L., Kamau E., Kirsch M., Pickard J.D., Owen A.M., Monti M.M. (2015) Thalamic and extra-thalamic mechanisms of consciousness after severe brain injury. Annals of Neurology. [ePub ahead of print].
Traditionally the thalamo-cortical axis is believed to be crucial for the maintenance/recovery of consciousness after brain injury as well as cortical/behavioral arousal. Evan Lutkenhoff (MontiLab post-doc) shows, in a paper now in press in Annals of Neurology, that while the degree of thalamic atrophy is proportional to a patient’s inability to produce voluntary behavior and communicate, the impairment in arousal is unrelated to thalamic atrophy. Rather, level of arousal was connected to the degree of atorphy within the basal ganglia (putamen/globus pallidus).
Atrophy in Patients as compared to Healthy Volunteers
Atrophy correlating with clinical scores of motor behavior/communication and arousal
A new MontiLab paper published in Neurology (IF: 8.3) demonstrating the importance of thalamo-frontal connectivity in cognitive function for patients with Disorders of Consciousness.
Monti M.M., Rosenberg M., Finoia P., Kamau E., Pickard J.D., Owen A.M. (2015) Thalamo-frontal connectivity mediates top-down cognitive functions in disorders of consciousness. Neurology, 85:1-7. [Pub ahead of print].
See also the accompanying Editorial by S. Goldman and N. Schiff.
Amy Zheng (GS 2nd year) and John Dell’Italia (GS 2nd year) have been awarded — last year and this year, respectively — an NSF Graduate Fellowship.